Article
Transcriptional Pre-patterning of Drosophila Gastrulation.
Current biology : CB - 23 Jan 2017
Lim Bomyi, Levine Michael, Yamazaki Yuji
Abstract excerpt
Gastrulation of the Drosophila embryo is one of the most intensively studied morphogenetic processes in animal development [1-4]. Particular efforts have focused on the formation of the ventral furrow, whereby ∼1,000 presumptive mesoderm cells exhibit coordinated apical constrictions that mediate invagination [5, 6]. Apical constriction depends on a Rho GTPase signaling pathway (T48/Fog) that is deployed by the...
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