Article
Balancing different types of actin polymerization at distinct sites: roles for Abelson kinase and Enabled.
The Journal of cell biology - 22 Dec 2003
Grevengoed Elizabeth E, Fox Donald T, Gates Julie, Peifer Mark
Abstract excerpt
The proto-oncogenic kinase Abelson (Abl) regulates actin in response to cell signaling. Drosophila Abl is required in the nervous system, and also in epithelial cells, where it regulates adherens junction stability and actin organization. Abl acts at least in part via the actin regulator Enabled (Ena), but the mechanism by which Abl regulates Ena is unknown. We describe a novel role for Abl in early Drosophila...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
