Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The human mu-opioid receptor gene polymorphism 118A > G decreases cortical activation in response to specific nociceptive stimulation.

Behavioral neuroscience - 1 Dec 2006

Lötsch Jörn, Stuck Boris, Hummel Thomas

Abstract excerpt

The authors sought to investigate the role of a common single nucleotide polymorphism in the mu-opioid receptor gene (OPRM1) 118A > G for nociceptive sensory processing using event-related potentials (ERPs). Specific nociceptive (carbon dioxide [CO-sub-2]: 40% volume-to-volume [vol/vol] and 60% v...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carbon Dioxide
Share to Cerebral Cortex
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dose-Response Relationship, Drug

Share to Evoked Potentials

Share to Reaction Time

Share to Receptors, Opioid, mu

Source

Identifiers

PMID: 17201465
DOI: 10.1037/0735-7044.120.6.1218

Genes

OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17201465-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The human mu-opioid receptor gene polymorphism 118A > G decreases cortical activation in response to specific nociceptive stimulation.PMID 17201465Read ↗

A common human micro-opioid receptor genetic variant diminishes the receptor signaling efficacy in brain regions processing the sensory information of pain.Semantic proximity Read ↗

Polymorphism of the micro-opioid receptor gene (OPRM1 118A>G) affects fentanyl-induced analgesia during anesthesia and recovery.Semantic proximity Read ↗

The A118G single nucleotide polymorphism of the mu-opioid receptor gene (OPRM1) is associated with pressure pain sensitivity in humans.Semantic proximity Read ↗

The mu-opioid receptor gene polymorphism 118A>G depletes alfentanil-induced analgesia and protects against respiratory depression in homozygous carriers.Semantic proximity Read ↗

Pharmacological consequence of the A118G μ opioid receptor polymorphism on morphine- and fentanyl-mediated modulation of Ca²⁺ channels in humanized mouse sensory neurons.Semantic proximity Read ↗

The μ-opioid receptor gene polymorphism 118A>G weakens the pharmacological action of buprenorphine.Semantic proximity Read ↗

µ-opioid receptor gene variant OPRM1 118 A>G: a summary of its molecular and clinical consequences for pain.Semantic proximity Read ↗

Meta-analysis of the relevance of the OPRM1 118A>G genetic variant for pain treatment.Semantic proximity Read ↗

A118G Mu Opioid Receptor polymorphism increases inhibitory effects on CaV2.2 channels.Semantic proximity Read ↗

Polymorphism of Opioid Receptors μ1 in Highly Hypnotizable Subjects.Semantic proximity Read ↗

The human μ-opioid receptor gene polymorphism (A118G) is associated with head pain severity in a clinical cohort of female migraine with aura patients.Semantic proximity Read ↗

Association between human μ‐opioid receptor gene polymorphism, pain tolerance, and opioid addictionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.