Article
Relative susceptibility of SJL/J and B10.S mice to experimental allergic encephalomyelitis is correlated with high and low responsiveness to myelin basic protein.
Journal of neuroimmunology - 1 Dec 1991
Binder T A, Clark R B, Goldschneider I
Abstract excerpt
SJL/J mice are highly susceptible to actively induced experimental allergic encephalomyelitis (EAE), whereas B10.S mice are not. Yet both strains share the H-2s major histocompatibility complex (MHC) haplotype. In order to help determine the cellular basis for the disparate susceptibility to EAE,...
Topics
- Animals
- Cell Division
- Encephalomyelitis, Autoimmune, Experimental
- Epitopes
- Female
- Genetic Predisposition to Disease
- Indicator Dilution Techniques
- Lymph Nodes
- Male
- Mice
- Mice, Inbred Strains
- Mice, Neurologic Mutants
- Myelin Basic Protein
- T-Lymphocytes
- T-Lymphocytes, Regulatory