Article
Experimental allergic encephalomyelitis in susceptible and resistant strains of mice after adoptive transfer of T cells activated by antibodies to the T cell receptor complex.
Journal of neuroimmunology - 1 Sept 1992
Zhao M L, Xia J Q, Fritz R B
Abstract excerpt
Lymphoid cells from normal and myelin basic protein (MBP)-immune PL/J, SJL/J and (SJL x PL)F1 hybrid mice were activated by in vitro culture with monoclonal antibodies specific for CD3 or specific T cell receptor (TCR) V beta chains. Lymphoid cells activated in this manner from MBP-immune animals...
Topics
- Animals
- Antibodies
- Antibodies, Monoclonal
- Concanavalin A
- Encephalomyelitis, Autoimmune, Experimental
- Genetic Predisposition to Disease
- Lymphocyte Activation
- Mice
- Mice, Inbred C57BL
- Mice, Mutant Strains
- Myelin Basic Protein
- Receptors, Antigen, T-Cell
- T-Lymphocytes