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Article

Lack of association of BRAF mutation with negative prognostic indicators in papillary thyroid carcinoma: the University of California, San Francisco, experience.

JAMA otolaryngology-- head & neck surgery - 1 Nov 2013

Gouveia Christopher, Can Nhu Thuy, Bostrom Alan, Grenert James P, van Zante Annemieke, Orloff Lisa A

Abstract excerpt

IMPORTANCE: Papillary thyroid carcinoma (PTC) is the most common endocrine neoplasm. B-type raf kinase (BRAF) V600E mutation has been proposed as a negative prognostic indicator in PTC, and patients harboring it should receive more aggressive initial therapy. OBJECTIVE: To assess the significance of BRAF V600E mutation in PTC in the largest US sample to date. DESIGN: We identified patients from our institution's...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24030686
DOI: 10.1001/jamaoto.2013.4501

Genes

BRAF

Variants

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