Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Persistence of Tumor Infiltrating Lymphocytes in Adoptive Immunotherapy Correlates With Telomere Length

19 Dec 2006

Abstract excerpt

Transfer of autologous tumor-specific tumor infiltrating lymphocytes (TILs) in adoptive immunotherapy can mediate the regression of tumor in patients with metastatic melanoma. In this procedure, TILs from resected tumors are expanded in vitro, then administered to patients and further stimulated to proliferate in vivo by the administration of high dose IL-2. After in vitro expansion, TILs are often dominated by a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immunotherapy and Immune Responses
Share to RNA Interference and Gene Delivery
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17198091
DOI: 10.1097/01.cji.0000211321.07654.b8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Persistence of Tumor Infiltrating Lymphocytes in Adoptive Immunotherapy Correlates With Telomere LengthPMID 17198091Read ↗

Telomere length of transferred lymphocytes correlates with in vivo persistence and tumor regression in melanoma patients receiving cell transfer therapy.Semantic proximity Read ↗

Survival, persistence, and progressive differentiation of adoptively transferred tumor-reactive T cells associated with tumor regression.Semantic proximity Read ↗

Tissue homing and persistence of defined antigen-specific CD8+ tumor-reactive T-cell clones in long-term melanoma survivors.Semantic proximity Read ↗

Persistence of multiple tumor-specific T-cell clones is associated with complete tumor regression in a melanoma patient receiving adoptive cell transfer therapy.Semantic proximity Read ↗

Selective Growth, In Vitro and In Vivo, of Individual T Cell Clones from Tumor-Infiltrating Lymphocytes Obtained from Patients with MelanomaSemantic proximity Read ↗

Transferred melanoma-specific CD8+ T cells persist, mediate tumor regression, and acquire central memory phenotype.Semantic proximity Read ↗

Comparative studies of the long-term growth of lymphocytes from tumor infiltrates, tumor-draining lymph nodes, and peripheral blood by repeated in vitro stimulation with autologous tumor.Semantic proximity Read ↗

Characteristics and in vivo homing of long-term T-cell lines and clones derived from tumor-draining lymph nodes.Semantic proximity Read ↗

The In vivo Expansion Rate of Properly Stimulated Transferred CD8+ T Cells Exceeds That of an Aggressively Growing Mouse TumorSemantic proximity Read ↗

Long-term culture of monoclonal human T lymphocytes: models for immunosenescence?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.