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Article

Telomere length of transferred lymphocytes correlates with in vivo persistence and tumor regression in melanoma patients receiving cell transfer therapy.

Journal of immunology (Baltimore, Md. : 1950) - 15 Nov 2005

Zhou Juhua, Shen Xinglei, Huang Jianping, Hodes Richard J, Rosenberg Steven A, Robbins Paul F

Abstract excerpt

Recent studies have indicated that adoptive immunotherapy with autologous antitumor tumor-infiltrating lymphocytes (TILs) following nonmyeloablative chemotherapy mediates tumor regression in approximately 50% of treated patients with metastatic melanoma, and that tumor regression is correlated with the degree of persistence of adoptively transferred T cells in peripheral blood. These findings, which suggested...

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Source

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Identifiers

PMID: 16272366
DOI: 10.4049/jimmunol.175.10.7046
PMCID: PMC1351312

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Telomere length of transferred lymphocytes correlates with in vivo persistence and tumor regression in melanoma patients receiving cell transfer therapy.PMID 16272366Read ↗

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