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Article

Tissue homing and persistence of defined antigen-specific CD8+ tumor-reactive T-cell clones in long-term melanoma survivors.

The Journal of investigative dermatology - 1 Mar 2007

Le Gal Frédérique-Anne, Widmer Valérie M, Dutoit Valérie, Rubio-Godoy Verena, Schrenzel Jacques, Walker Paul R, Romero Pedro J, Valmori Danila, Speiser Daniel E, Dietrich Pierre-Yves

Abstract excerpt

Tumor antigen-specific cytotoxic T cells (CTLs) play a major role in the adaptive immune response to cancers. This CTL response is often insufficient because of functional impairment, tumor escape mechanisms, or inhibitory tumor microenvironment. However, little is known about the fate of given tumor-specific CTL clones in cancer patients. Studies in patients with favorable outcomes may be very informative. In...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17039243
DOI: 10.1038/sj.jid.5700580

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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