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Article

The pharmacogenetics of medications used in general anesthesia.

Pharmacogenomics - 1 Feb 2018

Xie Shangchen, Ma Wenjuan, Guo Qulian, Liu Jie, Li Wei, McLeod Howard L, He Yijing

Abstract excerpt

General anesthesia is a state of unconsciousness, amnesia, analgesia and akinesia induced by drugs including opioids, hypnotic-sedative agents, muscle relaxants and antiemetics. Clinical and genetic factors are reported to influence the efficacy and side effects of these agents. Based on the evidence, clinical action is needed to improve clinical outcomes. This review summarizes the latest knowledge with regards...

Topics

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Anesthesia, General
Drug-Related Side Effects and Adverse Reactions
Pharmacogenetics
Polymorphism, Single Nucleotide

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 29318929
DOI: 10.2217/pgs-2017-0168

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