DNA hypomethylation and germ cell-specific expression of testis-specific H2B histone gene.

doi:10.1016/s0021-9258(18)54953-x

Article

DNA hypomethylation and germ cell-specific expression of testis-specific H2B histone gene.

1 Oct 1991

Abstract excerpt

Testis-specific H2B (TH2B) histone gene of rat is expressed during meiotic event of spermatogenic differentiation. The gene is unusual in that it has conserved the regulatory elements involved in the S phase-specific transcription of somatic H2B genes as well as the S phase-specific stabilization of histone mRNA. Genomic sequencing revealed that all analyzed CpG sites in the promoter region of TH2B gene are...

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