Article
Relationship of SNP of H2BFWT gene to male infertility in a Chinese population with idiopathic spermatogenesis impairment.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Aug 2012
Ying Hou-qun, Scott Matthew B, Zhou-Cun A
Abstract excerpt
The H2B family, member W, testis specific (H2BFWT) gene encodes a testis specific histone that plays a crucial role in reorganization and remodeling of chromatin and epigenetic regulation during spermatogenesis, suggesting that the gene may be involved in spermatogenesis impairment. To test the speculation, the allele and haplotype frequencies of two single-nucleotide polymorphism loci in this gene, -9C>T and...
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