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Histone acetylation regulated by histone deacetylases during spermatogenesis

12 Aug 2024

Abstract excerpt

BACKGROUND: Physical, chemical, and biological factors in the environment constantly influence in vivo and in vitro biological processes, including diverse histone modifications involved in cancer and metabolism. However, the intricate mechanisms of acetylation regulation remain poorly elucidated. In mammalian spermatogenesis, acetylation plays a crucial role in repairing double-strand DNA breaks, regulating gene...

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PMID: 39132925
DOI: 10.1111/andr.13723

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