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Article

Elucidation of the role of peptide linker in calcium-sensing receptor activation process.

The Journal of biological chemistry - 23 Feb 2007

Ray Kausik, Adipietro Kaylin A, Chen Claudia, Northup John K

Abstract excerpt

Family 3 G-protein-coupled receptors (GPCRs), which includes metabotropic glutamate receptors (mGluRs), sweet and "umami" taste receptors (T1Rs), and the extracellular calcium-sensing receptor (CaR), represent a distinct group among the superfamily of GPCRs characterized by large amino-terminal extracellular ligand-binding domains (ECD) with homology to bacterial periplasmic amino acid-binding proteins that are...

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Identifiers

PMID: 17189274
DOI: 10.1074/jbc.M609610200

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ECD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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