Article
Ultrasensitive in situ label-free DNA detection using a GaN nanowire-based extended-gate field-effect-transistor sensor.
Analytical chemistry - 15 Mar 2011
Chen Chin-Pei, Ganguly Abhijit, Lu Ching-Ying, Chen Ting-Yu, Kuo Chun-Chiang, Chen Reui-San, Tu Wen-Hsun, Fischer Wolfgang B, Chen Kuei-Hsien, Chen Li-Chyong
Abstract excerpt
In this study, we have successfully demonstrated that a GaN nanowire (GaNNW) based extended-gate field-effect-transistor (EGFET) biosensor is capable of specific DNA sequence identification under label-free in situ conditions. Our approach shows excellent integration of the wide bandgap semiconducting nature of GaN, surface-sensitivity of the NW-structure, and high transducing performance of the EGFET-design. The...
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