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Alterations in cell proliferation and apoptosis in colon cancers with microsatellite instability

22 Dec 2006

Abstract excerpt

Colon cancers with microsatellite instability (MSI) demonstrate a host immune response characterized by tumor infiltrating lymphocytes (TILs) that may exert effects upon tumor cell apoptosis and cell proliferation. Accordingly, we compared rates of apoptosis and cell proliferation in colon cancers with defective DNA mismatch repair and their association with phenotypic features and clinical outcome. Primary...

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PMID: 17187355
DOI: 10.1002/ijc.22429

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