Article
Multiple ADH genes modulate risk for drug dependence in both African- and European-Americans.
Human molecular genetics - 15 Feb 2007
Luo Xingguang, Kranzler Henry R, Zuo Lingjun, Wang Shuang, Schork Nicholas J, Gelernter Joel
Abstract excerpt
Drug dependence (DD) is commonly co-morbid with alcohol dependence (AD). Many studies have also shown common genetic risk factors for these disorders. We previously reported associations of AD with seven alcohol dehydrogenase (ADH) genes. The present study examines the relationship between these genes and DD. We genotyped 16 markers within the ADH gene cluster and 38 unlinked ancestry-informative markers in a...
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