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Article

A nucleotide sequence variation detection system for the core region of hepatitis C virus-1b.

Journal of virological methods - 1 Apr 2007

Okamoto Katsura, Akuta Norio, Kumada Hiromitsu, Kobayashi Mariko, Matsuo Yuki, Tazawa Hiromitsu

Abstract excerpt

Amino-acid substitution at positions 70 and 91 of the hepatitis C virus (HCV)-1b core region is a factor that contributes to a non-virological response in treatment using interferon/ribavirin combination. In this study, a system was developed for detection of nucleotide sequence variation in the core region that is simpler and less expensive than the current direct sequencing method. A PCR detection method using...

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Identifiers

PMID: 17184852
DOI: 10.1016/j.jviromet.2006.11.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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