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Article

Association between HCV amino acid substitutions and outcome of peginterferon and ribavirin combination therapy in HCV genotype 1b and high viral load.

Journal of gastroenterology and hepatology - 1 Jun 2010

Toyoda Hidenori, Kumada Takashi, Tada Toshifumi, Arakawa Takahiro, Hayashi Kazuhiko, Honda Takashi, Katano Yoshiaki, Goto Hidemi

Abstract excerpt

BACKGROUND AND AIM: We prospectively compared the sensitivity to interferon (IFN) and the efficacy of antiviral combination therapy with peginterferon (PEG-IFN) and ribavirin for chronic hepatitis C virus (HCV) genotype 1b infection according to the amino acid sequences of the HCV core, E1, and NS5A regions reported to be associated with the outcome of antiviral therapy. METHODS: A total of 107 patients with HCV...

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Source

Identifiers

PMID: 20594221
DOI: 10.1111/j.1440-1746.2010.06240.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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