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Article

Quantitation of substitutions at amino acid 70 in hepatitis C virus genotype 1b.

Virology journal - 15 Aug 2014

Hu Zhongjie, Liu Ying, Qiu Lixia, Fan Zuopeng, Nie Wei, Liang Shan, Jin Ronghua

Abstract excerpt

BACKGROUND: Substitutions of amino acid (aa) 70 in the core region of hepatitis C virus genotype 1b (HCV 1b) are a predictor of the non-virological response to pegylated interferon plus ribavirin (PEG-IFN/RBV) therapy. The aim of our study was to develop quantitative real-time reverse transcription polymerase chain reaction (qPCR) assays to quantify wild-type (70 W) and mutant (70 M) strains of HCV 1b. METHODS:...

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Identifiers

PMID: 25128407
DOI: 10.1186/1743-422X-11-148
PMCID: PMC4141953

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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