Article
Amino acid substitutions in the hepatitis C virus core region of genotype 1b affect very early viral dynamics during treatment with telaprevir, peginterferon, and ribavirin.
Journal of medical virology - 1 Apr 2010
Akuta Norio, Suzuki Fumitaka, Hirakawa Miharu, Kawamura Yusuke, Yatsuji Hiromi, Sezaki Hitomi, Suzuki Yoshiyuki, Hosaka Tetsuya, Kobayashi Masahiro, Kobayashi Mariko, Saitoh Satoshi, Arase Yasuji, Ikeda Kenji, Kumada Hiromitsu
Abstract excerpt
Substitution of amino acid (aa) 70 and 91 in the core region of hepatitis C virus (HCV) genotype 1b can predict the response to pegylated interferon (PEG-IFN)/ribavirin combination therapy, but its impact on triple therapy of telaprevir/PEG-IFN/ribavirin is not clear. The aims of this study were...
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