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Article

Are transversion mutations better? A Mutagenesis Assistant Program analysis on P450 BM-3 heme domain.

Biotechnology journal - 1 Jan 2007

Wong Tuck Seng, Roccatano Danilo, Schwaneberg Ulrich

Abstract excerpt

Directed evolution represents a versatile tool to tailor enzyme properties to needs in industrial applications and to understand structure-function relationships. Genetic diversity is commonly generated using error-prone PCR. Exploration of sequence space by random mutagenesis strongly favors transitions when enzyme-based mutagenesis methods are employed (Wong, T. S., Zhurina, D., Schwaneberg, U., Comb. Chem....

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Identifiers

PMID: 17183510
DOI: 10.1002/biot.200600201

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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