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Article

A P450 BM-3 mutant hydroxylates alkanes, cycloalkanes, arenes and heteroarenes.

Journal of biotechnology - 15 Jun 2001

Appel D, Lutz-Wahl S, Fischer P, Schwaneberg U, Schmid R D

Abstract excerpt

P450 monooxygenases from microorganisms, similar to those of eukaryotic mitochondria, display a rather narrow substrate specificity. For native P450 BM-3, no other substrates than fatty acids or an indolyl-fatty acid derivative have been reported (Li, Q.S., Schwaneberg, U., Fischer, P., Schmid, R.D., 2000. Directed evolution of the fatty-acid hydroxylase P450BM-3 into an indole-hydroxylating catalyst. Chem. Eur....

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PMID: 11403851
DOI: 10.1016/s0168-1656(01)00249-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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