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Article

Shuffling the Neutral Drift of Unspecific Peroxygenase in Saccharomyces cerevisiae.

Applied and environmental microbiology - 1 Aug 2018

Martin-Diaz Javier, Paret Carmen, García-Ruiz Eva, Molina-Espeja Patricia, Alcalde Miguel

Abstract excerpt

Unspecific peroxygenase (UPO) is a highly promiscuous biocatalyst, and its selective mono(per)oxygenase activity makes it useful for many synthetic chemistry applications. Among the broad repertory of library creation methods for directed enzyme evolution, genetic drift allows neutral mutations to be accumulated gradually within a polymorphic network of variants. In this study, we conducted a campaign of genetic...

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Identifiers

PMID: 29776931
DOI: 10.1128/AEM.00808-18
PMCID: PMC6052263

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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