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Article

Pathogenic aspects of dermatomyositis, polymyositis and overlap myositis.

Presse medicale (Paris, France : 1983) - 1 Apr 2011

Gherardi Romain K

Abstract excerpt

Inflammatory myopathies (IMs) often have distinct histopathologic features suggesting humorally mediated involvement of the microcirculation in dermatomyositis (DM), including early capillary deposition of the complement C5b-9 membranolytic attack complex (MAC) and secondary ischaemic changes; and CD8 T-cell-mediated and MHC1-restricted autoimmune attack of myofibers in polymyositis (PM) and inclusion body...

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Identifiers

PMID: 21376512
DOI: 10.1016/j.lpm.2010.12.013

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