Article
Immunohistochemical Phenotype of T Cells Invading Muscle in Inclusion Body Myositis.
Journal of neuropathology and experimental neurology - 19 Sept 2022
Matsubara Shiro, Suzuki Shigeaki, Komori Takashi
Abstract excerpt
Inclusion body myositis (IBM) is an inflammatory myopathy of aged people with poor response to therapy. To characterize muscle-invading inflammatory cells, we performed immunohistochemical and ultrastructural studies on muscle biopsies from 10 patients with IBM with durations of illness from 3 to 84 months. At the surface of muscle fibers, 79% and 48% of CD8+ cells were positive for killer cell lectin-like...
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