Article

Pathogenic autoantibody internalization in myositis

2024-01-17

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objectives</h4> Myositis is a heterogeneous family of autoimmune muscle diseases. As myositis autoantibodies recognize intracellular proteins, their role in disease pathogenesis has been unclear. This study aimed to determine whether myositis autoantibodies reach their autoantigen targets within muscle cells and disrupt the normal function of these proteins. <h4>Methods</h4> Confocal immunofl...

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Literature Corpus work: e0522ee1-1aa7-5a8d-ba61-163785a4aa4d
DOI: 10.1101/2024.01.15.24301339

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