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Article

Patterns of constitutive and IFN-gamma inducible expression of HLA class II molecules in human melanoma cell lines.

Immunogenetics - 1 Feb 2007

Rodríguez T, Méndez R, Del Campo A, Aptsiauri N, Martín J, Orozco G, Pawelec G, Schadendorf D, Ruiz-Cabello F, Garrido F

Abstract excerpt

Major histocompatibility complex (MHC) class II proteins (HLA-DR, HLA-DP and HLA-DQ) play a fundamental role in the regulation of the immune response. The level of expression of human leukocyte antigen (HLA) class II antigens is regulated by interferon-gamma (IFN-gamma) and depends on the status of class II trans-activator protein (CIITA), a co-activator of the MHC class II gene promoter. In this study, we...

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Source

Identifiers

PMID: 17180681
DOI: 10.1007/s00251-006-0171-9

Genes

CIITA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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