Article
Congenic strains confirm aerobic running capacity quantitative trait loci on rat chromosome 16 and identify possible intermediate phenotypes.
Physiological genomics - 14 Mar 2007
Ways Justin A, Smith Brian M, Barbato John C, Ramdath Ramona S, Pettee Krista M, DeRaedt Sarah J, Allison David C, Koch Lauren G, Lee Soon Jin, Cicila George T
Abstract excerpt
We previously identified two inbred rat strains divergent for treadmill aerobic running capacity (ARC), the low-performing Copenhagen (COP) and the high-performing DA rats, and used an F(2)(COPxDA) population to identify ARC quantitative trait loci (QTLs) on rat chromosome 16 (RNO16) and the proximal portion of rat chromosome 3 (RNO3). Two congenic rat strains were bred to further investigate these ARC QTLs by...
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