Article
Gene expression profiling of the left ventricles in a rat model of intrinsic aerobic running capacity.
Physiological genomics - 21 Sept 2005
Lee Soon Jin, Ways Justin A, Barbato John C, Essig David, Pettee Krista, DeRaedt Sarah J, Yang Siming, Weaver David A, Koch Lauren G, Cicila George T
Abstract excerpt
Our previous work found DA rats superior for intrinsic aerobic running capacity (ARC) and several cardiac function indexes compared with Copenhagen (COP) rats, and identified ARC quantitative trait loci (QTLs) on rat chromosomes 16 (RNO16) and 3 (RNO3). The purpose of this study was to use these inbred rat strains as a genetic substrate for differential cardiac gene expression to identify candidate genes for the...
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