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Article

<i>TCL1</i> targeting <i>miR-3676</i> is codeleted with tumor protein p53 in chronic lymphocytic leukemia

2 Feb 2015

Abstract excerpt

B-cell chronic lymphocytic leukemia (CLL) is the most common human leukemia and dysregulation of the T-cell leukemia/lymphoma 1 (TCL1) oncogene is a contributing event in the pathogenesis of the aggressive form of this disease based on transgenic mouse studies. To determine a role of microRNAs on the pathogenesis of the aggressive form of CLL we studied regulation of TCL1 expression in CLL by microRNAs. We...

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PMID: 25646413
DOI: 10.1073/pnas.1500010112

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<i>TCL1</i> targeting <i>miR-3676</i> is codeleted with tumor protein p53 in chronic lymphocytic leukemiaPMID 25646413Read ↗

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