Article
Genetic and Functional Analysis of Polymorphisms in the Human Dopamine Receptor and Transporter Genes in Small Cell Lung Cancer.
Journal of cellular physiology - 1 Feb 2016
Cherubini Emanuela, Di Napoli Arianna, Noto Alessia, Osman Giorgia Amira, Esposito Maria Cristina, Mariotta Salvatore, Sellitri Rossella, Ruco Luigi, Cardillo Giuseppe, Ciliberto Gennaro, Mancini Rita, Ricci Alberto
Abstract excerpt
The regulatory role of dopamine (DA) in endocrine, cardiovascular and renal functions has been extensively studied and used for clinical purposes. More recently DA has been indicated as a regulatory molecule for immune cells and malignant cell proliferation. We assessed the expression and the functional role DA, DA receptors, and transporters in primary small cell lung cancer (SCLC). By HPLC DA plasma levels were...
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