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Article

The role of IFNgamma nuclear localization sequence in intracellular function.

Journal of cell science - 1 Aug 2003

Ahmed C M Iqbal, Burkhart Marjorie A, Mujtaba Mustafa G, Subramaniam Prem S, Johnson Howard M

Abstract excerpt

Intracellularly expressed interferon gamma (IFNgamma) has been reported to possess biological activity similar to that of IFNgamma added to cells. This study addresses the mechanisms for such similar biological effects. Adenoviral vectors were used to express a non-secreted form of human IFNgamma or a non-secreted mutant form in which a previously demonstrated nuclear localization sequence (NLS), 128KTGKRKR134,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12799413
DOI: 10.1242/jcs.00528

Genes

IFNGR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The role of IFNgamma nuclear localization sequence in intracellular function.PMID 12799413Read ↗

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