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Article

Epitope mapping of human monoclonal antibodies to HLA-B27 by using natural and mutated antigenic variants.

Human immunology - 1 Aug 1991

Weyl D, Hansen T, Deschamps Y, Hannestad K, Toubert A

Abstract excerpt

The epitopes defined by three human monoclonal antibodies (mAbs) (Tr3B6, TrCG10, TrBH12) against HLA-B27 have been mapped by flow cytometry. For this purpose we used murine transfected cells expressing at their surface hybrid antigens between HLA-B7 and -B27 and, in addition, Epstein-Barr virus cell lines expressing the six HLA-B27 alleles B*2701 to B*2706. The results indicated that the mAbs are domain specific....

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Source

Identifiers

PMID: 1717416
DOI: 10.1016/0198-8859(91)90099-u

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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