Article
Epitope mapping of an HLA-B27 monoclonal antibody that also reacts with a 35-kD bacterial outer-membrane protein.
Clinical and experimental immunology - 1 Oct 1990
Toubert A, Hamachi M, Raffoux C, Park M S, Yu D T
Abstract excerpt
Ye-3 is an HLA-B27-specific murine monoclonal antibody recognizing the heat-modifiable protein of Enterobacteriaceae. Here we used recombinant hybrid molecules between the HLA-B7 and HLA-B27 antigens to delineate the epitope recognized by Ye-3. Results of these experiments indicated that the segm...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- Bacterial Outer Membrane Proteins
- Blotting, Western
- Enterobacteriaceae
- Epitopes
- HLA-B27 Antigen
- HLA-B7 Antigen
- Humans
- Mice
- Mice, Inbred BALB C
- Recombinant Fusion Proteins
- Transfection