A DR7 specific monoclonal antibody TAL13.1, raised against a transfectant detects IL-4 upregulated antigen on peripheral B-lymphocytes.

doi:10.1111/j.1744-313x.1991.tb00037.x

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Article

A DR7 specific monoclonal antibody TAL13.1, raised against a transfectant detects IL-4 upregulated antigen on peripheral B-lymphocytes.

European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Jan 2000

Heyes J M, Marsh S G, Sadler A M, Madrigal J A, Bodmer J G

Abstract excerpt

A monoclonal antibody TAL13.1 was raised against mouse L cells transfected with the human HLA-DRB1*0701 gene. This antibody was found to be polymorphic recognizing a determinant expressed by the DR7, DRB1*0701 and DRB1*0702 gene products. Four polymorphic sites unique to this specificity have been identified within the DR beta 1 domain. These are residues 11-14, 25, 30 and 71-74, one or a combination of which is...

Topics

Alleles
Amino Acid Sequence
Animals
Antibodies, Monoclonal
Antibody Specificity
B-Lymphocytes
Epitopes
HLA-DR7 Antigen
Humans
In Vitro Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Interleukin-4

Mice

Molecular Sequence Data

Polymorphism, Genetic

Recombinant Proteins

Sequence Alignment

Transfection

Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 1722998
DOI: 10.1111/j.1744-313x.1991.tb00037.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1722998-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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