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Article

Main approaches to target discovery and validation.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2007

Sioud Mouldy

Abstract excerpt

The identification and validation of disease-causing target genes is an essential first step in drug discovery and development. Genomics and proteomics technologies have already begun to uncover novel functional pathways and therapeutic targets in several human diseases such as cancers and autoimmunity. Also, bioinformatics approaches have highlighted several key targets and functional networks. In contrast to...

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PMID: 17172722
DOI: 10.1385/1-59745-165-7:1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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