Article
Emerging high-throughput drug target validation technologies.
Drug discovery today - 15 Sept 2002
Ilag Leodevico L, Ng Jocelyn H, Beste Gerald, Henning Stefan W
Abstract excerpt
Identifying the right target for drug development is a critical bottleneck in the pharmaceutical and biotech industries. The genomics revolution has shifted the problem from a scarcity of targets to a surplus of putative drug targets. As the validity of a target cannot be simply inferred from correlative data, the key is confirmation of the causative role of a gene product in a particular disease. It should...
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