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Article

In vivo target validation using gene invalidation, RNA interference and protein functional knockout models: it is the time to combine.

Current opinion in pharmacology - 1 Oct 2009

Vidalin Olivier, Muslmani Machadiya, Estienne Clément, Echchakir Hamid, Abina Amine M

Abstract excerpt

Most diseases have multifactorial origins and their study requires complex in vivo validation strategies selected for their particular relevance. Most of the in vivo models used to date have been selected according to their availability and the accessibility of the corresponding technology platfo...

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Identifiers

PMID: 19646923
DOI: 10.1016/j.coph.2009.06.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19646923-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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