Article
Growth factor-dependent regulation of survivin by c-myc in human breast cancer
1 Dec 2006
Abstract excerpt
Survivin has emerged as a unique regulator of cell death through its response to growth factors, such as basic fibroblast growth factor (bFGF), which we have previously shown to be mitogen-activated protein kinase (MAPK) dependent. The transcriptional complex myc/max is an oncogene that lies downstream of the MAPK pathway, suggesting a possible role in survivin's regulation. In this study, we investigated the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
