Article
Mutations, mutation rates, and evolution at the hypervariable VNTR loci of Yersinia pestis.
Mutation research - 1 Mar 2007
Vogler Amy J, Keys Christine E, Allender Christopher, Bailey Ira, Girard Jessica, Pearson Talima, Smith Kimothy L, Wagner David M, Keim Paul
Abstract excerpt
VNTRs are able to discriminate among closely related isolates of recently emerged clonal pathogens, including Yersinia pestis the etiologic agent of plague, because of their great diversity. Diversity is driven largely by mutation but little is known about VNTR mutation rates, factors affecting mutation rates, or the mutational mechanisms. The molecular epidemiological utility of VNTRs will be greatly enhanced...
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