Article
Features of Variable Number of Tandem Repeats in Yersinia pestis and the Development of a Hierarchical Genotyping Scheme.
PloS one - 1 Jan 2013
Li Yanjun, Cui Yujun, Cui Baizhong, Yan Yanfeng, Yang Xianwei, Wang Haidong, Qi Zhizhen, Zhang Qingwen, Xiao Xiao, Guo Zhaobiao, Ma Cong, Wang Jing, Song Yajun, Yang Ruifu
Abstract excerpt
BACKGROUND: Variable number of tandem repeats (VNTRs) that are widely distributed in the genome of Yersinia pestis proved to be useful markers for the genotyping and source-tracing of this notorious pathogen. In this study, we probed into the features of VNTRs in the Y. pestis genome and developed a simple hierarchical genotyping system based on optimized VNTR loci. METHODOLOGY/PRINCIPAL FINDINGS: Capillary...
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