Article
Effect of repeat copy number on variable-number tandem repeat mutations in Escherichia coli O157:H7.
Journal of bacteriology - 1 Jun 2006
Vogler Amy J, Keys Christine, Nemoto Yoshimi, Colman Rebecca E, Jay Zack, Keim Paul
Abstract excerpt
Variable-number tandem repeat (VNTR) loci have shown a remarkable ability to discriminate among isolates of the recently emerged clonal pathogen Escherichia coli O157:H7, making them a very useful molecular epidemiological tool. However, little is known about the rates at which these sequences mutate, the factors that affect mutation rates, or the mechanisms by which mutations occur at these loci. Here, we...
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