Article
Mutation rates of spoligotypes and variable numbers of tandem repeat loci in Mycobacterium tuberculosis.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2010
Reyes Josephine F, Tanaka Mark M
Abstract excerpt
Variable numbers of tandem repeat (VNTR) loci and spoligotypes are molecular markers used to study genetic diversity of bacteria such as Mycobacterium tuberculosis. Knowledge about the rate at which molecular fingerprints change, or the mutation rate, is important for interpreting molecular epidemiological data and for studying quantitative models of the evolution and epidemiology of bacteria. In this paper we...
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