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Article

Effect of mu-opioid receptor gene polymorphisms on heroin-induced subjective responses in a Chinese population.

Biological psychiatry - 1 Jun 2007

Zhang Dandan, Shao Chunhong, Shao Minhua, Yan Pengrong, Wang Yi, Liu Yixiao, Liu Wenhong, Lin Tong, Xie Yuying, Zhao Yingnan, Lu Daru, Li Yifeng, Jin Li

Abstract excerpt

BACKGROUND: Genetic factors that influence subjective responses to drug use (such as euphoria) contribute to the risk of addiction. mu-opioid receptor is the molecular target of heroin mediating its effects in both pain relief and euphoria. METHODS: To evaluate the association of mu-opioid receptor gene (OPRM1) variants with heroin-induced positive responses on first use, we studied 336 Chinese Han heroin addicts...

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Source

Identifiers

PMID: 17157823
DOI: 10.1016/j.biopsych.2006.07.012

Genes

OPRM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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