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Article

Senataxin: A key actor in RNA metabolism, genome integrity and neurodegeneration.

Biochimie - 1 Feb 2024

Giannini Marta, Porrua Odil

Abstract excerpt

The RNA/DNA helicase senataxin (SETX) has been involved in multiple crucial processes related to genome expression and integrity such us transcription termination, the regulation of transcription-replication conflicts and the resolution of R-loops. SETX has been the focus of numerous studies since the discovery that mutations in its coding gene are the root cause of two different neurodegenerative diseases:...

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PMID: 37558082
DOI: 10.1016/j.biochi.2023.08.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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Senataxin: A key actor in RNA metabolism, genome integrity and neurodegeneration.PMID 37558082Read ↗

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