Article
Glycosylation deficiency phenotypes resulting from depletion of GDP-mannose pyrophosphorylase in two yeast species.
Molecular microbiology - 1 Jun 2000
Warit S, Zhang N, Short A, Walmsley R M, Oliver S G, Stateva L I
Abstract excerpt
The genes encoding GDP-mannose pyrophosphorylase from Saccharomyces cerevisiae (SRB1/PSA1) and Candida albicans (CaSRB1) were expressed under the control of the tightly regulated promoters of MET3 and CaMET3 respectively. Northern analysis showed that the addition of methionine effectively blocks the transcription of pMET3-SRB1/PSA1 and pCaMET3CaSRB1 expression cassettes, which had been integrated into the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
