Article
Escaping from the TGFbeta anti-proliferative control.
Carcinogenesis - 1 Nov 2006
Seoane Joan
Abstract excerpt
Transforming growth factor-beta (TGFbeta) has a crucial role in tissue homeostasis and disruption of the TGFbeta pathway has been implicated in many human diseases including cancer. As a potent inhibitor of epithelial cell proliferation, TGFbeta is a tumor suppressor. Tumor cells evade the antitu...
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