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Molecular and Structural Bases for the Antigenicity of VP2 of Infectious Bursal Disease Virus

20 Sept 2007

Abstract excerpt

Infectious bursal disease virus (IBDV), a member of the family Birnaviridae, is responsible for a highly contagious and economically important disease causing immunosuppression in chickens. IBDV variants isolated in the United States exhibit antigenic drift affecting neutralizing epitopes in the capsid protein VP2. To understand antigenic determinants of the virus, we have used a reverse-genetics approach to...

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PMID: 17881448
DOI: 10.1128/jvi.01501-07

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