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Article

Genetic mechanisms of antigenic variation in infectious bursal disease virus: analysis of a naturally occurring variant virus.

Virus genes - 1 Aug 1992

Lana D P, Beisel C E, Silva R F

Abstract excerpt

The major immunogenic protein VP2 from a pathogenic field isolate (variant A virus) of infectious bursal disease virus (IBDV) was cloned and sequenced to examine antigenic variations. The VP2 open reading frame consists of 1509 nucleotides and codes for a 503 amino acid protein. Overall, the VP2 amino acid sequence of the variant A virus shares 98.6% identity with VP2 genes from other published IBDV strains....

Topics

Amino Acid Sequence
Animals
Antigenic Variation
Base Sequence
Capsid
Capsid Proteins
Chickens
Cloning, Molecular
DNA, Viral
Genetic Variation
Infectious bursal disease virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

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Identifiers

PMID: 1329340
DOI: 10.1007/BF01702563

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1329340-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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